Brain diseases such as stroke, dementia, and depression have more in common than previously thought, according to a new study published in the Journal of Neurology, Neurosurgery and Psychiatry.
Researchers from Massachusetts General Hospital’s Brain Care Labs analyzed data from 59 previous studies and identified 17 factors that increase the risk of these conditions, many of which are linked to everyday habits and routines.
The team reported that at least 60% of strokes, 40% of dementia cases, and 35% of late-life depression diagnoses are tied to lifestyle-related risks.
These include high blood pressure, severe kidney disease, obesity, blood sugar, cholesterol, alcohol use, diet, hearing loss, pain, physical activity, purpose in life, sleep, smoking, social engagement, stress, and lack of leisure activities such as puzzles.
Senior researcher Dr. Sanjula Singh noted that there are numerous ways individuals can lower their risk, such as improving diet, exercising regularly, and addressing high blood pressure.
Lead researcher Dr. Jasper Senff pointed out that these diseases are interconnected, meaning that lowering one’s chance of developing any single condition can reduce vulnerability to others.
The research team hopes to use these results to refine their existing Brain Care Score, which is designed to guide people in protecting their cognitive health.
Dr. Jonathan Rosand, chair of neurology at Massachusetts General Hospital, described the findings as a reminder that many common ailments share similar risk factors.
According to Rosand, focusing on these shared elements can help older Americans take charge of their well-being and potentially reduce the burden of several age-related brain diseases at once.
Experts caution that failing to address these risk factors can leave individuals exposed to several serious conditions that often occur together.
Although more research is needed, these findings indicate that ignoring common health concerns could lead to a greater likelihood of stroke, dementia, and depression in later life, with potentially severe consequences for personal independence and overall well-being.